What it is: A clean, concentrated, clinically-proven serum that helps address deep wrinkles, rough texture, laxity and more. What it does: It's made with three skin-renewing retinoids and a retinol plus collagen-boosting polypeptide to transform and renew skin and rapidly rejuvenate skin. Botanicals help soothe and protect. Research results: In an eight-week clinical study of 35 subjects ages 35–70: - 100% showed improvement in the look of deep wrinkles in just four weeks- 100% showed improvement in the look of facial pores in just four weeks- 100% showed improvement in hydration in just four weeksHow to use: Limit initial use to just three times per week, gradually increasing frequency to every night as tolerated. Mild redness, tingling or flaking is normal when starting a retinoid protect. If skin discomfort persists, reduce frequency or discontinue use. Wear a broad-spectrum sunscreen daily. 1 oz. Paraben-free; phthalate-free; silicone-free; formaldehyde donor–free; SLS-free; SLES-free; PEG-free; polyacrylamide-free; TEA-free; DEA-free; synthetic fragrance–free Made in the USA